Background

Most of the adult population has metabolic dysfunction originating in chronic, high frequency consumption of processed food and carbohydrates. Some of those dysfunctions manifests in familiar problems: obesity, diabetes, high blood pressure, dementia, and more. These problems exact increasingly devastating individual and societal costs. Epidemic metabolic dysfunction is being addressed with solutions from counting calories through appetite suppressants to gastric bypass. All of them have shown little efficacy and a lot of side effects. 

discovery

Peptide number 19, “Pep19,” was discovered in fat layers of mammals when exterior temperature dropped below 10 Celsius. Pep19 binds to receptors that trigger thermogenesis, the mechanism that is triggered by cold. It commands fat to metabolize itself for energy. Pep19 receptors for this peptide are found in fat layers of mammals, including humans.

In humans, they also exist in intra-abdominal visceral fat, which is associated with serious adverse outcomes in diseases ranging from cardiovascular disease to COVID-19 infection. The oral consumption of Pep19 reduces body fat and/or prevents fat accumulation and favorably regulates metabolic and anatomic parameters linked to type 2 diabetes, excess body fat, and others.

Regulation

Pep19 as a natural peptide exists in micro quantities in foods, including hibiscus, papaya, meat, and others, It is a very stable peptide that can sustain transport through the gut. Pep19 can withstand boiling, cooking, baking, and freezing. It is not toxic or allergenic.

Pep19 operates only in white fat tissue; it does not get through the blood-brain barrier. Accordingly, it has no effect on the brain and does not affect appetite, mood, or behavior.


Proteimax is commercializing Pep19 as a food additive. The ability to provide a convenient, inexpensive, and non-toxic solution in the form of a functional food is a game changer for fat management. 

Pep19 has been certified Generally Recognized As Safe (GRAS), a regulatory status reserved only to food grade molecules. Based on its voluminous characterization, the company has also received status as a Preferred Supplier to the National Animal Supplement Council.

Products

In early 2023, Pep19 was formulated into 5 mg capsules by one of the the partners. These capsules are available online as the nutroslim brand. 

By formulating Pep19 into bars, snacks, cookies, beverages and more, Pep19 holds the promise to turn them into food that doesn’t make you fat.